Does an Anti-Inflammatory Diet Help With Perimenopause Symptoms?
If you're in your 40s and Googling “what to eat for perimenopause”, you're not alone.
Everywhere you turn, there's someone shouting about food rules: only eat during a 6-hour window, cut out sugar completely, go gluten-free, eat only purple foods on Tuesdays (kidding, but barely). It’s overwhelming. And confusing. And most of it? Not backed by actual science.
That’s why so many women end up in my DMs saying: “I just want someone to tell me what actually works.”
As a registered dietitian with a Master’s in Nutrition and an advanced certification in integrative and functional nutrition, I’ve spent almost a decade studying the research, testing what’s practical in real life, and supporting women through the chaos of midlife hormones. So let’s talk about one of the most common questions I get: does an anti-inflammatory diet actually help with perimenopause?
What Is an Anti-Inflammatory Diet?
An anti-inflammatory diet is not about eliminating everything—it’s about reducing the load on your body. That starts with:
Whole, minimally processed foods
Healthy fats (think olive oil, avocado, nuts, seeds, fatty fish)
Plenty of fiber from fruits, veggies, whole grains, and legumes
Herbs and spices with anti-inflammatory compounds
Limited added sugar, refined carbs, and ultra-processed snacks
In other words: this isn’t about expensive powders or eliminating entire food groups. It’s about getting back to basics—and supporting your body through one of its most significant transitions.
This approach is popular in wellness circles, but it’s also deeply rooted in research. Inflammation plays a role in everything from cardiovascular disease to brain health, and an anti-inflammatory diet has been linked to reduced chronic disease risk and improved overall well-being as we age (Cano et al., 2020).
The Assumption: Eating Anti-Inflammatory Foods Fixes Everything
Wouldn’t it be nice if one diet could just fix it all?
That’s the promise you hear in so many corners of wellness. And while anti-inflammatory eating can make a real impact, it’s not a magic bullet—and it’s not the only factor that matters.
Your genetics do play a role in how your body responds to inflammation, hormone shifts, and even how easily you gain or lose weight. But they’re not your destiny. In the world of epigenetics, your daily choices—what you eat, how you sleep, how you move, how you manage stress—actually influence how your genes show up and express themselves. So no, you can’t change your DNA. But you can change how your body responds to it. And that response? That’s where the real power lies.
That’s why supporting your hormones through perimenopause with anti-inflammatory foods can be so helpful. It gives your body less to fight against. It creates more stability. And for many women, that leads to fewer cravings, better energy, more regular digestion, and an easier time maintaining or losing weight (Byrne-Kirk et al., 2024).
Sam is a perfect example. She was in her early 50s—mom of three, full-time teacher, totally overwhelmed. Her cravings were intense, her energy was shot, and she was stuck at a weight that wouldn’t budge. When she joined the PEACE Method, we made a few targeted changes: more protein at breakfast; a boost in fiber; high-quality fats like olive oil, avocado, and fatty fish; fewer processed foods and sugars; and consistency with meals. We also added a fiber and omega-3 supplement and focused on stress management. Four months later, she had lost 20 pounds, her sweet cravings were almost gone, and she finally had energy to get through her workday without crashing. No extremes. Just real food, done consistently.
That said, if you’re navigating more complex health issues—like autoimmune conditions, insulin resistance, or high, unmanaged stress—diet alone may not be enough. But for most women, shifting toward a more whole-foods, less processed way of eating leads to real, tangible benefits. That’s what we focus on inside the PEACE Method: simple, sustainable changes that support your hormones, your energy, and your everyday life. Just like Sam experienced—when you commit to the process and stay consistent, things start to shift. You feel more like yourself again. And that feeling is everything.
How Inflammation Interacts With Perimenopausal Changes
Estrogen levels fluctuate dramatically in perimenopause, which can increase low-grade systemic inflammation. This can show up as:
Brain fog
Joint pain
Fatigue
Bloating
Weight gain
Mood swings
A 2024 review in Nutrients found that inflammation can both contribute to and result from hormonal shifts in perimenopause, impacting metabolic function, immune health, and even mental clarity (Goncalves et al., 2024). Other studies have linked higher inflammation markers like CRP and IL-6 with increased menopause symptoms and a higher risk of chronic disease in postmenopausal women (Vetrani et al., 2022).
Translation? Reducing inflammation might not eliminate your symptoms entirely, but it could make them less intense—and help you feel more stable, energized, and in control.
When an Anti-Inflammatory Diet Falls Short
Sometimes women start eating this way and feel… underwhelmed. They try it for a week or two, don’t see big changes, and give up.
But the reality is: this is a lifestyle shift, not a one-week reset. It takes time to reduce chronic inflammation, regulate your hormones, and see the ripple effect on symptoms like bloating, fatigue, and weight gain. That’s why so many of my clients in the PEACE Method see the most success—because they have accountability, guidance, and support to keep going when things feel slow or frustrating.
And let’s be honest: results only come when you’re consistent. If you’re still drinking wine most nights, skipping meals, loading your coffee with sugary creamers, or trying to offset stress with snacks... you may not get the outcomes you’re hoping for. You don’t have to be perfect (we don’t do all-or-nothing here). But you do need to be honest with yourself about how consistently you’re showing up.
There’s also the myth that “more is better.” But even with healthy foods, balance matters. Overdoing it on fruit can spike your blood sugar. A generous pour of olive oil can still add up. Nuts, seeds, avocados—they’re all incredibly nutritious, but portion size still counts, especially if weight loss is part of your goal.
And this isn’t one-size-fits-all. Maybe you have food allergies or strong preferences. Maybe your body needs a specific macronutrient breakdown to feel full and energized. That’s where working with a dietitian becomes so helpful—we can tailor this framework to you, so it’s not overwhelming or restrictive, but actually doable in your real life.
How to Experiment With Anti-Inflammatory Eating Safely
You don’t need to revamp your entire kitchen, meal plan, or life to get started with anti-inflammatory eating. In fact, trying to change everything at once is usually what makes people burn out. The goal here is to make a few simple upgrades at a time—and keep building on them.
Here’s what that might look like in real life:
Start with one or two meal upgrades per week.
You don’t need to meal prep for 10 hours on Sunday. Maybe it’s just adding salmon to dinner once a week. Or tossing some baby spinach into your eggs. Small changes can add up quickly. If you’re not sure where to start, check out my free 7-day Mood Boost Reset.Swap in avocado instead of butter or cream cheese on toast.
Add a sprinkle of chili flakes or hemp seeds if you want some extra flavor and fiber. Pair it with a hard-boiled egg or leftover grilled chicken for a more balanced meal.Aim for at least 5 colorful fruits or veggies daily.
This doesn’t mean raw carrots and celery sticks. Try:A mixed greens salad kit with added tomatoes, cucumbers, and olives
Roasted trays of veggies like broccoli, peppers, squash, sweet potatoes, and beets
A berry salad with blueberries, strawberries, and raspberries for the week
Blending spinach or cauliflower into a smoothie
Adding frozen butternut squash or zucchini to a soup or sauce
Add anti-inflammatory fats and fiber to your routine.
Sprinkle chia, flax, or hemp seeds into oatmeal, yogurt, or smoothies. Drizzle olive oil on roasted veggies. Snack on a handful of almonds with a piece of fruit.Choose smarter snacks.
Instead of chips or sugary granola bars, keep things like roasted chickpeas, edamame, or a homemade trail mix with raw nuts and dried fruit on hand. Even a slice of turkey wrapped around cucumber slices counts. [Download my free Snack Smarter Guide]Use what you already have.
This doesn’t have to mean a whole new grocery list. Most of my clients are busy working moms—we don’t have time for complicated recipes or elaborate shopping trips. Start with what’s already in your fridge. Maybe it’s upgrading your frozen pizza night with a side salad and some added frozen (steamed) veggies. Or swapping white rice for frozen quinoa or quick-cook farro when you can.
In my 1:1 program, the PEACE Method, we track these changes through photo food journaling and symptom logs. This lets us catch patterns quickly—maybe you feel more bloated after having dairy, or your energy dips when lunch is light on protein. Instead of guessing, we collaborate and make targeted adjustments that work for your body.
And we don’t make it miserable. This isn’t about eating bland chicken and steamed kale. Meals should taste good and feel satisfying. Some client favorites include:
Warm oatmeal topped with Greek yogurt, berries, walnuts, and cinnamon
A salad kit with grilled organic chicken and pre-cooked farro or quinoa
Roasted salmon with sweet potatoes and broccoli, drizzled with olive oil and lemon
Tofu or black bean tacos with avocado, cabbage slaw, and salsa
Smoothies with frozen berries, flaxseed, spinach, and protein powder
The bottom line: you don’t need a perfect meal plan—you need a repeatable rhythm that feels good. And if you're not sure what that looks like for you? That’s exactly where a dietitian can help.
What Improvements You Might Notice (and When)
This isn’t a 10-day detox. And it’s not going to “fix” everything overnight. But it will create momentum—if you give it time.
One of the first things many of my clients notice is a shift in their energy - and this happens pretty quickly with just a few small changes. Instead of dragging through the afternoon or crashing at 8 p.m., they start to feel more even—less wired-tired, more grounded and clear-headed. That’s often followed by improvements in digestion (less bloating, more regularity), fewer sugar cravings, better sleep, and less reactive moods.
These might sound like small wins, but they matter. They’re the building blocks of a body that feels more in sync. And once those changes start stacking up, it becomes easier to make better choices because you’re no longer running on empty or constantly chasing a quick fix.
From a research perspective, some of these shifts can start showing up within just a few weeks. For example, studies have shown that dietary patterns rich in anti-inflammatory nutrients (like omega-3s, fiber, and polyphenols) can reduce inflammatory markers like CRP and IL-6 in as little as 4–6 weeks—especially when paired with improvements in sleep and movement routines (Goncalves et al., 2024, Vetrani et al., 2022). Another study noted that improvements in mood and cognitive function linked to diet and gut health often appear after 6–8 weeks of consistent change, depending on baseline inflammation and individual health status (Cano et al., 2020).
In other words: these changes take time—but they are absolutely possible. And when they happen, they ripple into everything else.
Take Laura, for example. She came to me in the middle of early menopause, newly diagnosed with an autoimmune condition, and feeling like weight loss was completely out of reach. She felt bloated, exhausted, and overwhelmed. We didn’t do anything extreme—we just got strategic. We focused on increasing fiber (especially fruits and vegetables), prioritizing protein at every meal, cutting back on candy and processed snacks, increasing hydration, and choosing higher-quality fats and carbs.
By the end of our time together, she told me:
“I feel strong and in control. I was able to eat consistently healthy, which made me feel empowered and calm instead of anxious and out of control. That feeling is amazing and spills over into everything else in your life. Health and nutrition has become a part of my everyday life, decisions, and goals.”
It’s a powerful shift—and it’s one I see often. When women finally have a framework that works with their hormones and health (instead of fighting against them), they stop feeling stuck. They start feeling capable again.
And that’s where real change happens.
FAQs
Do I need to follow it 100%?
Nope. Perfection isn’t required. Progress is.
Will this help with weight gain?
For many women, yes—because it supports metabolism, balances blood sugar, and reduces inflammation. But it works best when paired with other healthy habits.
What if I still have symptoms?
Then we dig deeper—stress, sleep, gut health, thyroid, nutrient levels. Diet is a piece of the puzzle.
Can I still drink coffee or wine?
Coffee? Yes. But let’s look at what you’re putting in it.
Wine? Limit it. Sorry. But even cutting back to weekends can make a big difference.
How do I know if inflammation is an issue for me?
Common signs: fatigue, brain fog, weight gain, bloating, joint pain, GI issues.
Final Thoughts
An anti-inflammatory diet isn’t a magic fix—but for many women, it’s one of the most effective starting points for feeling better in perimenopause. Not just physically, but mentally and emotionally, too.
It’s not about being perfect. And it’s not about following rigid rules. It’s about learning how to nourish your body in a way that supports your hormones, calms inflammation, and helps you show up as your best self—in your work, in your relationships, and in your day-to-day life.
If you’re curious about trying this way of eating, start with realistic goals. Add in one or two upgrades a week. Track how you feel. Give it time. And know that support can make all the difference—especially when symptoms feel overwhelming or when you’re not sure what’s actually working.
Want an easy place to start? Download my free breakfast guide with anti-inflammatory ideas to start your day feeling steady and satisfied.
Or use this as a chance to reflect. Grab a notebook (or use your Notes app) and start tracking what you eat, how you feel, and what patterns you notice—because awareness is the first step toward lasting change.
And if you’re ready for support that’s customized to you, your schedule, and your symptoms—I’d love to help. The PEACE Method is my 1:1 coaching program designed to help women in midlife lose weight, feel more energized, and finally make sense of their nutrition. Together, we’ll build a plan that’s realistic, sustainable, and grounded in what works.
Schedule a free clarity call here to see if it’s the right fit.
Let’s get you feeling like yourself again—for real this time.
References:
DISCLAIMER: The information contained in this post is not, and should not be construed as, medical advice. It is provided for informational purposes only. Each individual’s situation, nutritional needs and medical situation are different, and the information contained in this post may not be appropriate for your personal situation. Always check with your own physician or medical professional before implementing any change to your lifestyle, food intake, exercise regimen or medical treatment.
(C) 2025 Schuster Nutrition, PLLC
Article written by Melissa Schuster, MS, RDN, CDN, IFNCP
Melissa Schuster is a Registered Dietitian and mom of two. She helps busy moms transform their relationship with food through concierge virtual coaching so they can feel fantastic, lose weight for good, and focus on the things that matter most. With her signature PEACE Method which takes a whole-person approach, Melissa has helped hundreds of women find lasting peace in their bodies and around food. An expert in nutrition, Melissa holds a Masters in Clinical Nutrition and Dietetics from New York University and an Integrative and Functional Nutrition Certification.
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